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Antibody-drug conjugates and cellular metabolic dynamics [[electronic resource] /] / edited by Shuqing Chen, Jinbiao Zhan
| Antibody-drug conjugates and cellular metabolic dynamics [[electronic resource] /] / edited by Shuqing Chen, Jinbiao Zhan |
| Edizione | [First edition 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (IX, 135 p. 1 illus.) |
| Disciplina | 571.96028 |
| Soggetto topico |
Biology—Technique
Experimental immunology Pharmaceutical chemistry Medicine—Research Biology—Research Cytology Clinical biochemistry Immunoconjugates Immunotherapy Immunologic Techniques Chemistry, Pharmaceutical Immunological Techniques Pharmaceutics Biomedical Research Cell Biology Medical Biochemistry |
| ISBN | 981-19-5638-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Antibody-Drug Conjugates Basic Concepts and Structures -- Relationship between target and specific action of antibody-drugs conjugates -- The internalization and therapeutic activity of antibody drug conjugate -- The internalization and intracellular trafficking of ADC -- Distribution and metabolism of antibody-drug conjugates -- Application of Antibody fragments in ADCs -- Novel Targeting Carriers in Antibody-drug Conjugates -- Site-specified Conjugating Technology and Application -- Determination of drug-to-antibody ratio of ADCs -- Pharmacokinetic study of antibody-drug conjugates. |
| Record Nr. | UNINA-9910698647603321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological and Clinical Landscape of Meningiomas [[electronic resource] /] / edited by Gelareh Zadeh, Roland Goldbrunner, Boris Krischek, Farshad Nassiri
| Biological and Clinical Landscape of Meningiomas [[electronic resource] /] / edited by Gelareh Zadeh, Roland Goldbrunner, Boris Krischek, Farshad Nassiri |
| Autore | Zadeh Gelareh |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (264 pages) |
| Disciplina | 616.99481 |
| Altri autori (Persone) |
GoldbrunnerRoland
KrischekBoris NassiriFarshad |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine—Research
Biology—Research Biomedical Research |
| ISBN | 3-031-29750-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Introduction and History of Meningiomas -- Chapter 2. Clinical Presentation and Prognosis -- Chapter 3. Imaging Characteristics of Meningiomas -- Chapter 4. Histopathology of Meningiomas -- Chapter 5. Skull Base Meningiomas -- Chapter 6. Spinal Meningiomas -- Chapter 7. Surgical Therapies -- Chapter 8. Radiation Therapies -- Chapter 9. Illustrative Cases -- Chapter 10. Advances in CNS Tumor Classification -- Chapter 11. Genomic Landscape -- Chapter 12. Radiation-Induced Meningiomas -- Chapter 13. Meningioma Predisposing Syndromes -- Chapter 14. Epigentic Landscape -- Chapter 15. Immune Profile -- Chapter 16. PDX Models/Mouse Models/Cell Lines -- Chapter 17. Novel Medical Therapies -- Chapter 18. Quality of Life in Menigioma Patients -- Chapter 19. Illustrative Cases: Revisited with Adjuvant Molecular Data -- Chapter 20. Future Directions in Management. |
| Record Nr. | UNINA-9910734824403321 |
Zadeh Gelareh
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Biology of mRNA: Structure and Function [[electronic resource] /] / edited by Marlene Oeffinger, Daniel Zenklusen
| The Biology of mRNA: Structure and Function [[electronic resource] /] / edited by Marlene Oeffinger, Daniel Zenklusen |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (318 pages) |
| Disciplina | 572.88 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine—Research
Biology—Research Molecular genetics Proteins Neurosciences Post-translational modification Biomedical Research Molecular Genetics Protein Biochemistry Neuroscience Post-translational Modifications RNA |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-31434-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Regulation of co-transcriptional mRNP assembly -- mRNA export through the NPC -- Roles of mRNA modifications in gene regulation -- Studying mRNPs using single molecule approaches -- Difference between mRNPs and lncRNAs? -- RNPs and/or sequence motives in mRNA localization -- mRNP structure -- New RNA binding proteins: mRNP composition -- Aggregation of repeats RNAs in neurodegenerative diseases -- mRNA structural organization and translation -- How to decide to make an mRNA - degradation -- Methods to study mRNP composition -- mRNA-DNA kisses – R-loops -- Forms of mRNA editing and their role in disease. |
| Record Nr. | UNINA-9910373908303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers in Toxicology [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy, Rajkumar Rajendram
| Biomarkers in Toxicology [[electronic resource] /] / edited by Vinood B. Patel, Victor R. Preedy, Rajkumar Rajendram |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (1160 pages) |
| Disciplina | 610.28 |
| Collana | Biomarkers in Disease: Methods, Discoveries and Applications |
| Soggetto topico |
Biochemical markers
Toxicology Medicine—Research Biology—Research Pharmacology Forensic sciences Biomarkers Medical Toxicology Biomedical Research Forensic Science |
| ISBN | 3-031-07392-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Markers of liver toxicity and biomarkers -- Biomarkers of kidney toxicity. -Biomarkers of cardiac toxicity: microRNA and beyond.-Biomarkers of gastrointestinal toxicity -- Biomarkers of skin toxicity -- Skeletal muscle biomarkers in toxicity studies -- Bone markers of toxicity -- biochemical markers of brain damage -- DNA adducts as biomarkers of nutritional toxicity -- Biomarkers of pollution toxicity: measuring heavy metals in blood -- Challenge-comet assay: applications to toxicity -- Alkylation adducts of nucleic acids as a biomarkers .-TGx-DDI transcriptomic biomarker: Features and applications.-DNA biomarkers: an updated narrative -- CRISPR/Cas9 Whole-Genome Screens: applications to environmental pollutants.-Apoptotic biomarkers in toxicity studies -- 5'UTR methylation as a biomarkers: investigating volatile organics -- 5-Fluorouracil degradation rate and a biomarker of capecitabine toxicity -- Investigating the blood-brain barrier as a marker of toxicology -- Biomarkers of oxidative stress: investigating apigenin -- Histology as a biomarker in toxicity: applications to investigating Syzygium guineense -- Hair metabolomics and biomarker discovery .-Markers of hepatotoxicity using metabolomics: applications to MDMA, ecstasy -- 1H-NMR metabolomics and biomarkers of myotoxins -- Nanoparticle-induced toxicity and transcriptomics as a biomarker discovery platform -- Urine metabolomics and biomarker discovery.-microRNA profiling as a biomarker platform: carcinogens and beyond. |
| Record Nr. | UNINA-9910647783003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomedical Simulation [[electronic resource] ] : 5th International Symposium, ISBMS 2010, Phoenix, AZ, USA, January 23-24, 2010. Proceedings / / edited by Fernando Bello, Stéphane Cotin
| Biomedical Simulation [[electronic resource] ] : 5th International Symposium, ISBMS 2010, Phoenix, AZ, USA, January 23-24, 2010. Proceedings / / edited by Fernando Bello, Stéphane Cotin |
| Edizione | [1st ed. 2010.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2010 |
| Descrizione fisica | 1 online resource (X, 193 p.) |
| Disciplina | 610.28 |
| Collana | Theoretical Computer Science and General Issues |
| Soggetto topico |
Computer simulation
Medicine—Research Biology—Research Radiology Computer vision Computer graphics Bioinformatics Computer Modelling Biomedical Research Computer Vision Computer Graphics Computational and Systems Biology |
| ISBN |
1-280-38558-8
9786613563507 3-642-11615-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Soft Tissue Properties -- LASTIC: A Light Aspiration Device for in vivo Soft TIssue Characterization -- Characterization of Suction and CUSA Interaction with Brain Tissue -- Evaluation of a Technique to Estimate the Compliance of Atherosclerotic Intima -- Quantifying Mechanical Properties in a Murine Fracture Healing System Using an Inverse Geometric Nonlinear Elasticity Modeling Framework -- Modeling and Segmentation -- Optimization of Case-Specific Vascular Tree Models Based on Vessel Size Imaging -- Efficient Generation of Corresponding Meshes for Biomedical Flow Simulations -- Solid Mesh Registration for Radiotherapy Treatment Planning -- Physics-Based Modeling of the Pregnant Woman -- Semi-automatic Segmentation of Fractured Pelvic Bones for Surgical Planning -- Simulation of Biophysical Processes -- Development of a Computer Simulation Tool for Application in Adolescent Spinal Deformity Surgery -- A Fluid-Structure Interaction Index of Coronary Plaque Rupture -- Biomechanical Simulation of Human Eye Movement -- A Theoretical Model for RF Ablation of Kidney Tissue and Its Experimental Validation -- A Point-Based Simulation Framework for Minimally Invasive Surgery -- Real-Time Interactive Simulation -- Six Degree-of Freedom Haptic Rendering for Dental Implantology Simulation -- Haptic Simulator for Prostate Brachytherapy with Simulated Ultrasound -- A Shell Model for Real-Time Simulation of Intra-ocular Implant Deployment -- Endovascular Guidewire Flexibility Simulation -- Comparing Automatic Simulator Assessment with Expert Assessment of Virtual Surgical Procedures. |
| Record Nr. | UNISA-996465328103316 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Biomedical Simulation [[electronic resource] ] : 5th International Symposium, ISBMS 2010, Phoenix, AZ, USA, January 23-24, 2010. Proceedings / / edited by Fernando Bello, Stéphane Cotin
| Biomedical Simulation [[electronic resource] ] : 5th International Symposium, ISBMS 2010, Phoenix, AZ, USA, January 23-24, 2010. Proceedings / / edited by Fernando Bello, Stéphane Cotin |
| Edizione | [1st ed. 2010.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2010 |
| Descrizione fisica | 1 online resource (X, 193 p.) |
| Disciplina | 610.28 |
| Collana | Theoretical Computer Science and General Issues |
| Soggetto topico |
Computer simulation
Medicine—Research Biology—Research Radiology Computer vision Computer graphics Bioinformatics Computer Modelling Biomedical Research Computer Vision Computer Graphics Computational and Systems Biology |
| ISBN |
1-280-38558-8
9786613563507 3-642-11615-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Soft Tissue Properties -- LASTIC: A Light Aspiration Device for in vivo Soft TIssue Characterization -- Characterization of Suction and CUSA Interaction with Brain Tissue -- Evaluation of a Technique to Estimate the Compliance of Atherosclerotic Intima -- Quantifying Mechanical Properties in a Murine Fracture Healing System Using an Inverse Geometric Nonlinear Elasticity Modeling Framework -- Modeling and Segmentation -- Optimization of Case-Specific Vascular Tree Models Based on Vessel Size Imaging -- Efficient Generation of Corresponding Meshes for Biomedical Flow Simulations -- Solid Mesh Registration for Radiotherapy Treatment Planning -- Physics-Based Modeling of the Pregnant Woman -- Semi-automatic Segmentation of Fractured Pelvic Bones for Surgical Planning -- Simulation of Biophysical Processes -- Development of a Computer Simulation Tool for Application in Adolescent Spinal Deformity Surgery -- A Fluid-Structure Interaction Index of Coronary Plaque Rupture -- Biomechanical Simulation of Human Eye Movement -- A Theoretical Model for RF Ablation of Kidney Tissue and Its Experimental Validation -- A Point-Based Simulation Framework for Minimally Invasive Surgery -- Real-Time Interactive Simulation -- Six Degree-of Freedom Haptic Rendering for Dental Implantology Simulation -- Haptic Simulator for Prostate Brachytherapy with Simulated Ultrasound -- A Shell Model for Real-Time Simulation of Intra-ocular Implant Deployment -- Endovascular Guidewire Flexibility Simulation -- Comparing Automatic Simulator Assessment with Expert Assessment of Virtual Surgical Procedures. |
| Record Nr. | UNINA-9910484150403321 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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CADD and Informatics in Drug Discovery [[electronic resource] /] / edited by Mithun Rudrapal, Johra Khan
| CADD and Informatics in Drug Discovery [[electronic resource] /] / edited by Mithun Rudrapal, Johra Khan |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (370 pages) |
| Disciplina | 615.1900285 |
| Collana | Interdisciplinary Biotechnological Advances |
| Soggetto topico |
Biology
Bioinformatics Medicine—Research Biology—Research Pharmacy Drugs—Design Biotechnology Biological Sciences Biomedical Research Structure-Based Drug Design |
| ISBN |
9789819913169
9789819913152 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1: Fundamentals of Computational Drug Design Approaches (CADD) -- Chapter 2: Molecular and Computational Modeling in Drug Design -- Chapter 3: Bioinformatics/Chemo-informatics Tools and Database in Drug Discovery -- Chapter 4: Computational Screening of Phytochemicals/Natural Products in Drug Discovery -- Chapter 5: Virtual Screening in Lead Discovery and Optimization -- Chapter 6: Target-based Screening (SBDD) in Lead Discovery -- Chapter 7: Pharmacophore-based and Similarity Search (LBDD) Screening in Lead Discovery -- Chapter 8: Receptor-based De Novo and Fragment-based Drug Design -- Chapter 9: Artificial Intelligence and Machine Learning in Drug Discovery -- Chapter 10: Network Pharmacology and System Biology Approaches -- Chapter 11: In Silico Pharmacology and Drug Repurposing Approaches -- Chapter 12: Advances in Bioinformatics and Computational Approaches in Drug Discovery -- Chapter 13: Challenges in Bioinformatics and Computational Approaches in Drug Discovery. |
| Record Nr. | UNINA-9910725088603321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical Research Informatics [[electronic resource] /] / edited by Rachel L. Richesson, James E. Andrews, Kate Fultz Hollis
| Clinical Research Informatics [[electronic resource] /] / edited by Rachel L. Richesson, James E. Andrews, Kate Fultz Hollis |
| Edizione | [3rd ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (519 pages) |
| Disciplina | 780 |
| Collana | Health Informatics |
| Soggetto topico |
Medical informatics
Public health administration Medicine—Research Biology—Research Health Informatics Health Administration Biomedical Research |
| ISBN | 3-031-27173-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to Clinical Research Informatics -- From Notations to Data: The Digital Transformation of Clinical Research -- Methodological Foundations of Clinical Research -- The Clinical Research Environment -- Biorepositories -- Study Protocol Representation -- Clinical Research Information Systems -- Public Policy Issues in Clinical Research Informatics -- Integrating EHR and Research -- Data Quality in Clinical Research -- Research Data Governance, Roles, and Infrastructure -- Informatics Approaches to Patient Recruitment -- Patient Registries for Clinical Research -- Managing clinical data/research data and phenotyping/cohort discovery -- Patient Reported Outcome Data -- Laboratory Data [New] -- Molecular, Genetic and other -omic Data -- Data Sharing: Clinical Trials Registries, Results Databases, and Research Data Repositories -- Knowledge Representation and Ontologies -- Developing and Promoting Data Standards for Clinical Research -- Non-Hypothesis Driven Research: Data mining and knowledge Discovery -- Advancing Clinical Research through Natural Language Processing on Electronic Health Records: Traditional Machine Learning Meets Deep Learning -- Back to the Future: The Evolution of Pharmacovigilance in the Age of Digital Healthcare -- The Evolving Role of Consumers -- Research in Open Environments -- Research in Context of Learning Health Systems. |
| Record Nr. | UNINA-9910731470703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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COVID-19 and Sleep: A Global Outlook [[electronic resource] /] / edited by Ahmed BaHammam, S. R. Pandi-Perumal, Haitham Jahrami
| COVID-19 and Sleep: A Global Outlook [[electronic resource] /] / edited by Ahmed BaHammam, S. R. Pandi-Perumal, Haitham Jahrami |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (XXVI, 430 p. 1 illus.) |
| Disciplina | 612.8 |
| Collana | Progress in Sleep Research |
| Soggetto topico |
Neurosciences
Public health Medicine—Research Biology—Research Neuroscience Public Health Biomedical Research |
| ISBN | 981-9902-40-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. The effect of sleep disruption and circadian misalignment on the immune system -- 2. Changes in the sleep and circadian pattern of sleep during the COVID-19 pandemic -- 3. Anxiety and depression during the COVID-19 pandemic and their impact on sleep -- 4. Sleep problems during the COVID-19 pandemic in children and adolescents -- 5.Sleep problems during the COVID-19 pandemic in children and adolescents -- 6. Sleep disturbances among healthcare workers during the COVID-19 pandemic -- 7. Sleep disturbances among patients with COVID-19 infection -- 8. Sleep patterns and sleep disturbances during the lockdown periods -- 9. Impact of COVID-19 Mobility Restrictions on Sleep and Wellbeing -- 10. COVID-19 vaccines and sleep disturbances -- 11. Sleep during the COVID-19 pandemic: structural inequity and racial disparity -- 12. The effect of cognitive-behavioral therapy and coping strategies on sleep disturbances during the COVID-19 pandemic -- 13. Sleep and circadian rhythm in post-COVID-19 patients -- 14. COVID-19 and obstructive sleep apnea -- 15. The correlation between COVID-19 infection and restless legs syndrome -- 16. Impact of COVID-19 pandemic lockdown on disorders of hypersomnolence -- 17. Sleep, Physical Activity, and Diet Patterns During COVID-19 Pandemic -- 18. Impact of screen time during the pandemic of COVID-19 on sleep habits -- 19. Dreams and nightmares during the COVID-19 pandemic -- 20. The impact of the COVID-19 pandemic on sleep medicine services -- 21. Protocols for conducting sleep studies during pandemics -- 22. Management of hospital and home positive airway pressure machines during pandemics -- 23. Telemedicine and telemonitoring of sleep disorders during the COVID-19 pandemic -- 24.Changes in Positive Airway Pressure Application and Practices in Patients with Sleep-Related Breathing Disorder during the COVID-19 Pandemic -- 25. Potential Therapeutic Effects of Melatonin on SARS-CoV-2 Infection. |
| Record Nr. | UNINA-9910717425003321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Data Monitoring Committees (DMCs) [[electronic resource] ] : Past, Present, and Future / / edited by Nand Kishore Rawat, David Kerr
| Data Monitoring Committees (DMCs) [[electronic resource] ] : Past, Present, and Future / / edited by Nand Kishore Rawat, David Kerr |
| Autore | Rawat Nand Kishore |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (113 pages) |
| Disciplina | 615.50724 |
| Altri autori (Persone) | KerrDavid |
| Soggetto topico |
Pharmacology
Medical sciences Drug development Medicine—Research Biology—Research Pharmaceutical chemistry Biometry Toxicology Preclinical Research Biomedical Research Pharmaceutics Biostatistics Medical Toxicology |
| ISBN | 3-031-28760-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions. |
| Record Nr. | UNINA-9910731469703321 |
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Rawat Nand Kishore
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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(33)
- Biomedical Research (32)
- Biotechnology (5)
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